Frank Lyko : rechercher sur Z-Library

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1

Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2

Durdevic, Zeljko, Hanna, Katharina, Gold, Beth, Pollex, Tim, Cherry, Sara, Lyko, Frank, Schaefer, Matthias

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 581 KB

english, 2013

2

Chromosomal elements conferring epigenetic inheritance

Frank Lyko, Renato Paro

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 149 KB

english, 1999

3

Insects as innovative models for functional studies of DNA methylation

Frank Lyko, Ryszard Maleszka

Journal:

Trends in Genetics

Année:

2011

Langue:

english

Fichier:

PDF, 175 KB

english, 2011

4

Selection of organic process and source indicator substances for the anthropogenically influenced water cycle

Jekel, Martin, Dott, Wolfgang, Bergmann, Axel, Dünnbier, Uwe, Gnirß, Regina, Haist-Gulde, Brigitte, Hamscher, Gerd, Letzel, Marion, Licha, Tobias, Lyko, Sven, Miehe, Ulf, Sacher, Frank, Scheurer, Marc

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2015

5

Aging and Chronic Sun Exposure Cause Distinct Epigenetic Changes in Human Skin

Grönniger, Elke, Weber, Barbara, Heil, Oliver, Peters, Nils, Stäb, Franz, Wenck, Horst, Korn, Bernhard, Winnefeld, Marc, Lyko, Frank, Reik, Wolf

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2010

6

Ein Krebs für die Krebsforschung

Journal:

Biologie in unserer Zeit

Année:

2017

Langue:

german

Fichier:

PDF, 945 KB

german, 2017

7

Mutations in Cytosine-5 tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats

Genenncher, Bianca, Durdevic, Zeljko, Hanna, Katharina, Zinkl, Daniela, Mobin, Mehrpouya Balaghy, Senturk, Nevcin, Da Silva, Bruno, Legrand, Carine, Carré, Clément, Lyko, Frank, Schaefer, Matthias

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 5.49 MB

english, 2018

8

Cooperative interactions between epigenetic modifications and their function in the regulation of chromosome architecture

Frank Weissmann, Frank Lyko

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 120 KB

english, 2003

9

Epigenetic cancer therapy: Proof of concept and remaining challenges

Cora Mund, Frank Lyko

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 311 KB

english, 2010

10

DNA methylation with a sting: An active DNA methylation system in the honeybee

Matthias Schaefer, Frank Lyko

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 107 KB

english, 2007

11

Molecular Modeling and Molecular Dynamics Studies of Hydralazine with Human DNA Methyltransferase 1

Narender Singh, Alfonso Dueñas-González, Frank Lyko, Jose L. Medina-Franco

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 660 KB

english, 2009

12

Quantitative analysis of DNA methylation in chronic lymphocytic leukemia patients

Frank Lyko, Dirk Stach, Axel Brenner, Stephan Stilgenbauer, Hartmut Döhner, Michaela Wirtz, Manfred Wiessler, Oliver J. Schmitz

Journal:

ELECTROPHORESIS

Année:

2004

Langue:

english

Fichier:

PDF, 92 KB

english, 2004

13

Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine

Carlo Stresemann, Frank Lyko

Journal:

International Journal of Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 214 KB

english, 2008

14

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation

Dirk Kuck, Narender Singh, Frank Lyko, Jose L. Medina-Franco

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 867 KB

english, 2010

15

Analysis of conditional gene deletion using probe based Real-Time PCR

Britta Weis, Joachim Schmidt, Frank Lyko, Heinz G Linhart

Journal:

BMC Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 881 KB

english, 2010

16

Analysis of conditional gene deletion using probe based Real-Time PCR

Britta Weis, Joachim Schmidt, Frank Lyko, Heinz G Linhart

Journal:

BMC Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 120 KB

english, 2010

17

Aberrant Epigenetic Silencing of Tumor Suppressor Genes Is Reversed by Direct Reprogramming

Shulamit Ron-Bigger, Ori Bar-Nur, Sara Isaac, Michael Bocker, Frank Lyko, Amir Eden

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 603 KB

english, 2010

18

Novel methods for analysis of genomic DNA methylation

Journal:

Analytical and Bioanalytical Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 140 KB

english, 2005

19

Stage-specific chromosomal association ofDrosophiladMBD2/3 during genome activation

Joachim Marhold, Marcin Zbylut, Dirk-Henner Lankenau, Mingfa Li, Daniel Gerlich, Esteban Ballestar, Bernard M. Mechler, Frank Lyko

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 442 KB

english, 2002

20

Solving the Dnmt2 enigma

Matthias Schaefer, Frank Lyko

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 199 KB

english, 2010

21

Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprintedH19/Igf2region inDrosophila

Sylvia Erhardt, Frank Lyko, Justin F-X. Ainscough, M. Azim Surani, Renato Paro

Journal:

Development Genes and Evolution

Année:

2003

Langue:

english

Fichier:

PDF, 358 KB

english, 2003

22

Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach

Jose L. Medina-Franco, Fabian López-Vallejo, Dirk Kuck, Frank Lyko

Journal:

Molecular Diversity

Année:

2011

Langue:

english

Fichier:

PDF, 721 KB

english, 2011

23

10.1038/15551

Jaenisch, Rudolf, Lyko, Frank, Ramsahoye, Bernard H., Kashevsky, Helena, Tudor, Matthew, Mastrangelo, Mary-Ann, Orr-Weaver, Terry L.

Journal:

Nature Genetics

Année:

1999

Langue:

english

Fichier:

PDF, 418 KB

english, 1999

24

10.1038/35046205

Jaenisch, Rudolf, Lyko, Frank, Ramsahoye, Bernard H.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2000

25

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation

Barreto, Guillermo, Schäfer, Andrea, Marhold, Joachim, Stach, Dirk, Swaminathan, Suresh K., Handa, Vikas, Döderlein, Gabi, Maltry, Nicole, Wu, Wei, Lyko, Frank

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 488 KB

english, 2007

26

An imprinting element from the mouse H19 locus functions as a silencer in Drosophila

Lyko, Frank, Brenton, James D., Surani, M. Azim, Paro, Renato

Journal:

Nature Genetics

Année:

1997

Fichier:

PDF, 395 KB

1997

27

Lack of evidence for DNA methylation of Invader4 retroelements in Drosophila and implications for Dnmt2-mediated epigenetic regulation

Schaefer, Matthias, Lyko, Frank

Journal:

Nature Genetics

Année:

2010

Langue:

english

Fichier:

PDF, 276 KB

english, 2010

28

Discovery of Two Novel, Small-Molecule Inhibitors of DNA Methylation

Siedlecki, Pawel, Boy, Regine Garcia, Musch, Tanja, Brueckner, Bodo, Suhai, Sandor, Lyko, Frank, Zielenkiewicz, Piotr

Journal:

Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 452 KB

english, 2006

29

Human fibroblast matrices bio-assembled under macromolecular crowding support stable propagation of human embryonic stem cells

Yanxian Peng, Michael Thomas Bocker, Jennifer Holm, Wei Seong Toh, Christopher Stephen Hughes, Fahad Kidwai, Gilles Andre Lajoie, Tong Cao, Frank Lyko, Michael Raghunath

Journal:

Journal of Tissue Engineering and Regenerative Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 927 KB

english, 2012

30

Two substrates are better than one: dual specificities for Dnmt2 methyltransferases

Albert Jeltsch, Wolfgang Nellen, Frank Lyko

Journal:

Trends in Biochemical Sciences

Année:

2006

Langue:

english

Fichier:

PDF, 232 KB

english, 2006

31

DNA methylation learns to fly

Journal:

Trends in Genetics

Année:

2001

Langue:

english

Fichier:

PDF, 244 KB

english, 2001

32

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

Tuorto, Francesca, Liebers, Reinhard, Musch, Tanja, Schaefer, Matthias, Hofmann, Sarah, Kellner, Stefanie, Frye, Michaela, Helm, Mark, Stoecklin, Georg, Lyko, Frank

Journal:

Nature Structural and Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 818 KB

english, 2012

33

DNA methyltransferase inhibitors: old and new drugs for an epigenetic cancer therapy

Bodo Brueckner, Frank Lyko

Journal:

Trends in Pharmacological Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 103 KB

english, 2004

34

Establishment and functional validation of a structural homology model for human DNA methyltransferase 1

Pawel Siedlecki, Regine Garcia Boy, Slobodan Comagic, Ralf Schirrmacher, Manfred Wiessler, Piotr Zielenkiewicz, Sandor Suhai, Frank Lyko

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 364 KB

english, 2003

35

Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster

Bocker, Michael T., Tuorto, Francesca, Raddatz, Günter, Musch, Tanja, Yang, Feng-Chun, Xu, Mingjiang, Lyko, Frank, Breiling, Achim

Journal:

Nature Communications

Année:

2012

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2012

36

LUMA (LUminometric Methylation Assay)—A high throughput method to the analysis of genomic DNA methylation

Mohsen Karimi, Sofia Johansson, Dirk Stach, Martin Corcoran, Dan Grandér, Martin Schalling, Georgy Bakalkin, Frank Lyko, Catharina Larsson, Tomas J. Ekström

Journal:

Experimental Cell Research

Année:

2006

Langue:

english

Fichier:

PDF, 269 KB

english, 2006

37

The putative Drosophila methyltransferase gene dDnmt2 is contained in a transposon-like element and is expressed specifically in ovaries

Frank Lyko, Allyson J Whittaker, Terry L Orr-Weaver, Rudolf Jaenisch

Journal:

Mechanisms of Development

Année:

2000

Langue:

english

Fichier:

PDF, 250 KB

english, 2000

38

The aging epigenome: DNA methylation from the cradle to the grave

Marc Winnefeld, Frank Lyko

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 171 KB

english, 2012

39

Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

Dawlaty, Meelad M., Breiling, Achim, Le, Thuc, Raddatz, Günter, Barrasa, M. Inmaculada, Cheng, Albert W., Gao, Qing, Powell, Benjamin E., Li, Zhe, Xu, Mingjiang, Faull, Kym F., Lyko, Frank, Jaenisch,

Journal:

Developmental Cell

Année:

2013

Langue:

english

Fichier:

PDF, 3.18 MB

english, 2013

40

The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers

Lyko, Frank, Foret, Sylvain, Kucharski, Robert, Wolf, Stephan, Falckenhayn, Cassandra, Maleszka, Ryszard, Keller, Laurent

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2010

41

The RNA Methyltransferase Dnmt2 Is Required for Efficient Dicer-2-Dependent siRNA Pathway Activity in Drosophila

Durdevic, Zeljko, Mobin, Mehrpouya Balaghy, Hanna, Katharina, Lyko, Frank, Schaefer, Matthias

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2013

42

Aging is associated with highly defined epigenetic changes in the human epidermis

Raddatz, Günter, Hagemann, Sabine, Aran, Dvir, Söhle, Jörn, Kulkarni, Pranav P, Kaderali, Lars, Hellman, Asaf, Winnefeld, Marc, Lyko, Frank

Journal:

Epigenetics & Chromatin

Année:

2013

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2013

43

Constrained Analogues of Procaine as Novel Small Molecule Inhibitors of DNA Methyltransferase-1

Castellano, Sabrina, Kuck, Dirk, Sala, Marina, Novellino, Ettore, Lyko, Frank, Sbardella, Gianluca

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 321 KB

english, 2008

44

Loss of Tet Enzymes Compromises Proper Differentiation of Embryonic Stem Cells

Dawlaty, Meelad M., Breiling, Achim, Le, Thuc, Barrasa, M. Inmaculada, Raddatz, Günter, Gao, Qing, Powell, Benjamin E., Cheng, Albert W., Faull, Kym F., Lyko, Frank, Jaenisch, Rudolf

Journal:

Developmental Cell

Année:

2014

Langue:

english

Fichier:

PDF, 3.71 MB

english, 2014

45

Identification of a Silencing Element in the Human 15q11-q13 Imprinting Center by Using Transgenic Drosophila

Frank Lyko, Karin Buiting, Bernhard Horsthemke and Renato Paro

Journal:

Proceedings of the National Academy of Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1998

46

Synthesis and in Vitro Evaluation of Biotinylated RG108: A High Affinity Compound for Studying Binding Interactions with Human DNA Methyltransferases

Schirrmacher, Esther, Beck, Carmen, Brueckner, Bodo, Schmitges, Frank, Siedlecki, Pawel, Bartenstein, Peter, Lyko, Frank, Schirrmacher, Ralf

Journal:

Bioconjugate Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 184 KB

english, 2006

47

Generalized Antisymmetrized Product Wave Functions for Atoms and Molecules

Parr, Robert G., Ellison, Frank O., Lykos, Peter G.

Journal:

The Journal of Chemical Physics

Année:

1956

Langue:

english

Fichier:

PDF, 326 KB

english, 1956

48

Methylation of Human MicroRNA Genes in Normal and Neoplastic Cells

Weber, Barbara, Stresemann, Carlo, Brueckner, Bodo, Lyko, Frank

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 407 KB

english, 2007

49

Dnmt3a Protects Active Chromosome Domains against Cancer-Associated Hypomethylation

Raddatz, Günter, Gao, Qing, Bender, Sebastian, Jaenisch, Rudolf, Lyko, Frank, Ren, Bing

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2012

50

RNA–Mediated Epigenetic Heredity Requires the Cytosine Methyltransferase Dnmt2

Kiani, Jafar, Grandjean, Valérie, Liebers, Reinhard, Tuorto, Francesca, Ghanbarian, Hossein, Lyko, Frank, Cuzin, François, Rassoulzadegan, Minoo, Bickmore, Wendy A.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2013